E3A (p.Glu3Ala) variant of PGR (Progesterone receptor)
E3A (p.Glu3Ala) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E3A (p.Glu3Ala) variant details
- p.Glu3Ala
- gnomAD rs1196735070
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.23
- CADD 26.00
- PolyPhen-2 0.71
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available