D116H (p.Asp116His) variant of PGR (Progesterone receptor)
D116H (p.Asp116His) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D116H (p.Asp116His) variant details
- p.Asp116His
- gnomAD rs1862985470
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.16
- CADD 25.00
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available