D107E (p.Asp107Glu) variant of PGR (Progesterone receptor)
D107E (p.Asp107Glu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D107E (p.Asp107Glu) variant details
- p.Asp107Glu
- ESP rs147932536
- ExAC rs147932536
- TOPMed rs147932536
- gnomAD rs147932536
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.16
- CADD 22.80
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available