C64S (p.Cys64Ser) variant of PGR (Progesterone receptor)
C64S (p.Cys64Ser) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
C64S (p.Cys64Ser) variant details
- p.Cys64Ser
- ExAC rs750407171
- gnomAD rs750407171
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.07
- CADD 19.30
- PolyPhen-2 0.01
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available