C64F (p.Cys64Phe) variant of PGR (Progesterone receptor)
C64F (p.Cys64Phe) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
C64F (p.Cys64Phe) variant details
- p.Cys64Phe
- cosmic curated COSV54809
- ExAC rs750407171
- gnomAD rs750407171
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.20
- CADD 24.40
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available