A92D (p.Ala92Asp) variant of PGR (Progesterone receptor)
A92D (p.Ala92Asp) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A92D (p.Ala92Asp) variant details
- p.Ala92Asp
- TOPMed rs1862991270
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.09
- CADD 22.30
- PolyPhen-2 0.73
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available