A6T (p.Ala6Thr) variant of PGR (Progesterone receptor)
A6T (p.Ala6Thr) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A6T (p.Ala6Thr) variant details
- p.Ala6Thr
- gnomAD rs1425983653
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.12
- CADD 23.40
- PolyPhen-2 0.39
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available