A15V (p.Ala15Val) variant of PGR (Progesterone receptor)
A15V (p.Ala15Val) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A15V (p.Ala15Val) variant details
- p.Ala15Val
- cosmic curated COSV54795
- TOPMed rs1328901959
- gnomAD rs1328901959
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.05
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available