A15E (p.Ala15Glu) variant of PGR (Progesterone receptor)
A15E (p.Ala15Glu) in PGR (Progesterone receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A15E (p.Ala15Glu) variant details
- p.Ala15Glu
- TOPMed rs1328901959
- gnomAD rs1328901959
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.07
- CADD 18.90
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 6.1e-05)
- Structural context available