K15N (p.Lys15Asn) variant of PDX1 (P52945)
K15N (p.Lys15Asn) in PDX1 (P52945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
K15N (p.Lys15Asn) variant details
- p.Lys15Asn
- ExAC rs747304604
- gnomAD rs747304604
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- REVEL 0.54
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available