S66T (p.Ser66Thr) variant of PDGFRB (P09619)
S66T (p.Ser66Thr) in PDGFRB (P09619) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S66T (p.Ser66Thr) variant details
- p.Ser66Thr
- ExAC rs747916560
- gnomAD rs747916560
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.02
- CADD 14.50
- PolyPhen-2 0.08
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available