S66F (p.Ser66Phe) variant of PDGFRB (P09619)
S66F (p.Ser66Phe) in PDGFRB (P09619) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S66F (p.Ser66Phe) variant details
- p.Ser66Phe
- TOPMed rs1277924406
- gnomAD rs1277924406
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.12
- CADD 23.20
- PolyPhen-2 0.83
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available