G32D (p.Gly32Asp) variant of PDGFRB (P09619)
G32D (p.Gly32Asp) in PDGFRB (P09619) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G32D (p.Gly32Asp) variant details
- p.Gly32Asp
- rs368010583
- ESP rs368010583
- ExAC rs368010583
- TOPMed rs368010583
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- AlphaMissense 0.08
- MetaLR 0.31
- MetaSVM -0.57
- PolyPhen-2 0.98
- SIFT 0.12
- EVE 0.20
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available