W32C (p.Trp32Cys) variant of PDCD1 (Programmed cell death protein 1)
W32C (p.Trp32Cys) in PDCD1 (Programmed cell death protein 1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
W32C (p.Trp32Cys) variant details
- p.Trp32Cys
- NCI-TCGA TCGA novel
- Ensembl rs2124861673
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.07
- MetaLR 0.14
- MetaSVM -0.99
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 0.15
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available