W23S (p.Trp23Ser) variant of PDCD1 (Programmed cell death protein 1)
W23S (p.Trp23Ser) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
W23S (p.Trp23Ser) variant details
- p.Trp23Ser
- ExAC rs753651738
- TOPMed rs753651738
- gnomAD rs753651738
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.21
- MetaLR 0.12
- MetaSVM -1.04
- CADD 20.20
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 3.4e-05)
- Structural context available