W23L (p.Trp23Leu) variant of PDCD1 (Programmed cell death protein 1)
W23L (p.Trp23Leu) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
W23L (p.Trp23Leu) variant details
- p.Trp23Leu
- ExAC rs753651738
- TOPMed rs753651738
- gnomAD rs753651738
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.22
- MetaLR 0.13
- MetaSVM -1.00
- CADD 16.70
- PolyPhen-2 0.42
- SIFT 0.12
- Population evidence available
- Structural context available