V11A (p.Val11Ala) variant of PDCD1 (Programmed cell death protein 1)
V11A (p.Val11Ala) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V11A (p.Val11Ala) variant details
- p.Val11Ala
- gnomAD rs1357299712
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.07
- MetaLR 0.13
- MetaSVM -1.01
- CADD 8.05
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Ashkenazi Jewish population (allele frequency 3.9e-05)
- Structural context available