T45A (p.Thr45Ala) variant of PDCD1 (Programmed cell death protein 1)
T45A (p.Thr45Ala) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T45A (p.Thr45Ala) variant details
- p.Thr45Ala
- Ensembl rs2124861435
- Missense
- Variant Prioritization Score for Impact Estimate 0.0952
- REVEL 0.07
- MetaLR 0.10
- MetaSVM -0.99
- CADD 0.13
- PolyPhen-2 0.00
- SIFT 0.75
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available