S60W (p.Ser60Trp) variant of PDCD1 (Programmed cell death protein 1)
S60W (p.Ser60Trp) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S60W (p.Ser60Trp) variant details
- p.Ser60Trp
- ExAC rs779874434
- TOPMed rs779874434
- gnomAD rs779874434
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.10
- MetaLR 0.14
- MetaSVM -1.01
- CADD 22.70
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available