S27Y (p.Ser27Tyr) variant of PDCD1 (Programmed cell death protein 1)
S27Y (p.Ser27Tyr) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
S27Y (p.Ser27Tyr) variant details
- p.Ser27Tyr
- ExAC rs756045758
- gnomAD rs756045758
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.16
- MetaLR 0.14
- MetaSVM -0.94
- CADD 5.27
- PolyPhen-2 0.27
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available