P35L (p.Pro35Leu) variant of PDCD1 (Programmed cell death protein 1)
P35L (p.Pro35Leu) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- TOPMed rs1700938702
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.10
- MetaLR 0.02
- MetaSVM -0.96
- CADD 8.96
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available