P28S (p.Pro28Ser) variant of PDCD1 (Programmed cell death protein 1)
P28S (p.Pro28Ser) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P28S (p.Pro28Ser) variant details
- p.Pro28Ser
- ExAC rs750373757
- gnomAD rs750373757
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.02
- MetaLR 0.11
- MetaSVM -1.02
- CADD 6.50
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available