P21S (p.Pro21Ser) variant of PDCD1 (Programmed cell death protein 1)
P21S (p.Pro21Ser) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P21S (p.Pro21Ser) variant details
- p.Pro21Ser
- ExAC rs754849604
- gnomAD rs754849604
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.03
- MetaLR 0.10
- MetaSVM -1.04
- CADD 12.40
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Latino/Admixed American population (allele frequency 2.4e-05)
- Structural context available