P21Q (p.Pro21Gln) variant of PDCD1 (Programmed cell death protein 1)
P21Q (p.Pro21Gln) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P21Q (p.Pro21Gln) variant details
- p.Pro21Gln
- TOPMed rs1388107514
- gnomAD rs1388107514
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.19
- MetaLR 0.14
- MetaSVM -0.96
- CADD 16.90
- PolyPhen-2 0.45
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available