N58D (p.Asn58Asp) variant of PDCD1 (Programmed cell death protein 1)
N58D (p.Asn58Asp) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
N58D (p.Asn58Asp) variant details
- p.Asn58Asp
- TOPMed rs1222512746
- gnomAD rs1222512746
- Missense
- Variant Prioritization Score for Impact Estimate 0.0955
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.02
- CADD 11.90
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available