N49S (p.Asn49Ser) variant of PDCD1 (Programmed cell death protein 1)
N49S (p.Asn49Ser) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
N49S (p.Asn49Ser) variant details
- p.Asn49Ser
- Ensembl rs2124861321
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.03
- MetaLR 0.14
- MetaSVM -1.00
- CADD 1.36
- PolyPhen-2 0.09
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available