L25V (p.Leu25Val) variant of PDCD1 (Programmed cell death protein 1)
L25V (p.Leu25Val) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L25V (p.Leu25Val) variant details
- p.Leu25Val
- gnomAD rs1192883440
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.12
- MetaLR 0.23
- MetaSVM -0.82
- CADD 18.20
- PolyPhen-2 0.98
- SIFT 0.08
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available