F63L (p.Phe63Leu) variant of PDCD1 (Programmed cell death protein 1)
F63L (p.Phe63Leu) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
F63L (p.Phe63Leu) variant details
- p.Phe63Leu
- ExAC rs781123013
- TOPMed rs781123013
- gnomAD rs781123013
- Missense
- Variant Prioritization Score for Impact Estimate 0.0951
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.02
- CADD 9.34
- PolyPhen-2 0.03
- SIFT 0.52
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available