F24L (p.Phe24Leu) variant of PDCD1 (Programmed cell death protein 1)
F24L (p.Phe24Leu) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
F24L (p.Phe24Leu) variant details
- p.Phe24Leu
- Ensembl rs2124872119
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.04
- MetaLR 0.04
- MetaSVM -0.99
- CADD 10.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.9e-05)
- Structural context available