A6P (p.Ala6Pro) variant of PDCD1 (Programmed cell death protein 1)
A6P (p.Ala6Pro) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A6P (p.Ala6Pro) variant details
- p.Ala6Pro
- Ensembl rs1033748408
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.13
- MetaLR 0.17
- MetaSVM -0.89
- CADD 16.70
- PolyPhen-2 0.44
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available