A40T (p.Ala40Thr) variant of PDCD1 (Programmed cell death protein 1)
A40T (p.Ala40Thr) in PDCD1 (Programmed cell death protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
A40T (p.Ala40Thr) variant details
- p.Ala40Thr
- Ensembl rs2124861525
- Missense
- Variant Prioritization Score for Impact Estimate 0.0831
- REVEL 0.03
- MetaLR 0.14
- MetaSVM -1.00
- CADD 2.44
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available