A45P (p.Ala45Pro) variant of PCDH15 (Protocadherin-15)
A45P (p.Ala45Pro) in PCDH15 (Protocadherin-15) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data.
A45P (p.Ala45Pro) variant details
- p.Ala45Pro
- gnomAD rs1338247790
- Missense
- Variant Prioritization Score for Impact Estimate 0.585
- MetaLR 0.10
- MetaSVM -1.04
- CADD 23.30
- PolyPhen-2 0.04
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 3e-05)