R22R (p.Arg22Arg) variant of PCCB (P05166)
R22R (p.Arg22Arg) in PCCB (P05166) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
R22R (p.Arg22Arg) variant details
- p.Arg22Arg
- rs759836996
- gnomAD 3-136250441-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.557
- CADD 8.60
- Most common in the African/African-American population (allele frequency 0.00017)
- Structural context available
- Literature evidence available