G166V (p.Gly166Val) variant of PBRM1 (Protein polybromo-1)
G166V (p.Gly166Val) in PBRM1 (Protein polybromo-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G166V (p.Gly166Val) variant details
- p.Gly166Val
- cosmic curated COSV99970
- ExAC rs781444225
- TOPMed rs781444225
- gnomAD rs781444225
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.04
- CADD 21.10
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available