G166R (p.Gly166Arg) variant of PBRM1 (Protein polybromo-1)
G166R (p.Gly166Arg) in PBRM1 (Protein polybromo-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G166R (p.Gly166Arg) variant details
- p.Gly166Arg
- cosmic curated COSV99970
- ExAC rs745942186
- TOPMed rs745942186
- gnomAD rs745942186
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.06
- CADD 21.80
- PolyPhen-2 0.09
- SIFT 0.40
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available