T85N (p.Thr85Asn) variant of PAX8 (Paired box protein Pax-8)
T85N (p.Thr85Asn) in PAX8 (Paired box protein Pax-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
T85N (p.Thr85Asn) variant details
- p.Thr85Asn
- ExAC rs772367877
- TOPMed rs772367877
- gnomAD rs772367877
- Missense
- Variant Prioritization Score for Impact Estimate 0.759
- REVEL 0.82
- CADD 24.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available