K91R (p.Lys91Arg) variant of PAX8 (Paired box protein Pax-8)
K91R (p.Lys91Arg) in PAX8 (Paired box protein Pax-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
K91R (p.Lys91Arg) variant details
- p.Lys91Arg
- Ensembl rs1691150484
- Missense
- Variant Prioritization Score for Impact Estimate 0.734
- REVEL 0.81
- CADD 26.50
- PolyPhen-2 0.50
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available