K87R (p.Lys87Arg) variant of PAX8 (Paired box protein Pax-8)
K87R (p.Lys87Arg) in PAX8 (Paired box protein Pax-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
K87R (p.Lys87Arg) variant details
- p.Lys87Arg
- Ensembl rs2104498416
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.62
- CADD 26.40
- PolyPhen-2 0.92
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available