R214S (p.Arg214Ser) variant of PAX6 (Paired box protein Pax-6)

R214S (p.Arg214Ser) in PAX6 (Paired box protein Pax-6) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as pathogenic in the context of Aniridia 1; Irido-corneo-trabecular dysgenesis. The record also includes published literature and structural context.

R214S (p.Arg214Ser) variant details