V69I (p.Val69Ile) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
V69I (p.Val69Ile) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
V69I (p.Val69Ile) variant details
- p.Val69Ile
- ExAC rs762887304
- TOPMed rs762887304
- gnomAD rs762887304
- Missense
- Variant Prioritization Score for Impact Estimate 0.065
- REVEL 0.06
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available