Q83R (p.Gln83Arg) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
Q83R (p.Gln83Arg) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
Q83R (p.Gln83Arg) variant details
- p.Gln83Arg
- ExAC rs748579213
- TOPMed rs748579213
- gnomAD rs748579213
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.14
- CADD 24.20
- PolyPhen-2 0.23
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available