K23N (p.Lys23Asn) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
K23N (p.Lys23Asn) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
K23N (p.Lys23Asn) variant details
- p.Lys23Asn
- gnomAD rs1185554480
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.12
- CADD 23.50
- PolyPhen-2 0.28
- SIFT 0.57
- Population evidence available
- Structural context available