I37V (p.Ile37Val) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
I37V (p.Ile37Val) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
I37V (p.Ile37Val) variant details
- p.Ile37Val
- TOPMed rs1285064497
- gnomAD rs1285064497
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.04
- CADD 21.00
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available