G96S (p.Gly96Ser) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
G96S (p.Gly96Ser) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G96S (p.Gly96Ser) variant details
- p.Gly96Ser
- Ensembl rs2102747102
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.12
- CADD 26.00
- PolyPhen-2 0.05
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available