D31H (p.Asp31His) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
D31H (p.Asp31His) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
D31H (p.Asp31His) variant details
- p.Asp31His
- ExAC rs756350417
- TOPMed rs756350417
- gnomAD rs756350417
- Missense
- Variant Prioritization Score for Impact Estimate 0.605
- REVEL 0.47
- CADD 31.00
- PolyPhen-2 0.91
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available