D100G (p.Asp100Gly) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
D100G (p.Asp100Gly) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
D100G (p.Asp100Gly) variant details
- p.Asp100Gly
- Ensembl rs1664835464
- Missense
- Variant Prioritization Score for Impact Estimate 0.1
- REVEL 0.06
- CADD 10.50
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available