A91V (p.Ala91Val) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
A91V (p.Ala91Val) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A91V (p.Ala91Val) variant details
- p.Ala91Val
- Ensembl rs2102747116
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.04
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available