A106T (p.Ala106Thr) variant of PARP1 (Poly [ADP-ribose] polymerase 1)
A106T (p.Ala106Thr) in PARP1 (Poly [ADP-ribose] polymerase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
A106T (p.Ala106Thr) variant details
- p.Ala106Thr
- ExAC rs771624359
- gnomAD rs771624359
- Missense
- Variant Prioritization Score for Impact Estimate 0.0413
- REVEL 0.02
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 0.63
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available