P66Q (p.Pro66Gln) variant of PARK7 (Parkinson disease protein 7)
P66Q (p.Pro66Gln) in PARK7 (Parkinson disease protein 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
P66Q (p.Pro66Gln) variant details
- p.Pro66Gln
- TOPMed rs1306142962
- gnomAD rs1306142962
- Missense
- Variant Prioritization Score for Impact Estimate 0.574
- REVEL 0.47
- CADD 22.60
- PolyPhen-2 0.02
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available