M26V (p.Met26Val) variant of PARK7 (Parkinson disease protein 7)
M26V (p.Met26Val) in PARK7 (Parkinson disease protein 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
M26V (p.Met26Val) variant details
- p.Met26Val
- TOPMed rs1417802320
- gnomAD rs1417802320
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- REVEL 0.57
- CADD 23.70
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available